Month: October 2021

An article Synthesis and properties of gem-dinitro energetic salts based on 1,2,4-oxadiazole with low impact sensitivity WOS:000609189100004 published article about HIGH-NITROGEN; DERIVATIVES; EXPLOSIVES in [Lu, Tian; He, Yuna; Song, Jia; Hou, Zhengwen; Yin, Hongquan; Chen, Fu-Xue] Beijing Inst Technol, Sch Chem Sc Chem Engn, Liangxiang Campus,8 Liangxiang East Rd, Beijing 102488, Peoples R China; [Fan, Guijuan] CAEP, Inst Chem Mat, Mianyang 621050, Sichuan, Peoples R China in 2021.0, Cited 37.0. The Name is 1,1,1-Triethoxyethane. Through research, I have a further understanding and discovery of 78-39-7. COA of Formula: C8H18O3

Eight energetic salts with a gem-dinitro group based on 1,2,4-oxadiazole were developed. All of the structures were confirmed by infrared (IR) spectroscopy, H-1 and C-13 nuclear magnetic resonance (NMR) spectroscopy, and high-resolution mass spectrometry (HRMS), and single-crystal X-ray diffraction was used to determine the structures of the pivotal intermediate 3-(chlorodinitromethyl)-5-methyl-1,2,4-oxadiazole (3), the potassium salt (4) and the hydrazinium salt (7). All of them are insensitive to impact (>40 J) and have higher energy levels than trinitrotoluene (TNT).

COA of Formula: C8H18O3. About 1,1,1-Triethoxyethane, If you have any questions, you can contact Lu, T; He, YN; Song, J; Hou, ZW; Yin, HQ; Fan, GJ; Chen, FX or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

In 2020.0 NAT PROD RES published article about NATURAL-PRODUCTS; STEREOCHEMISTRY in [Koziol, Agata; Fratczak, Jakub; Grela, Ewa; Lochynski, Stanislaw] Wroclaw Univ Sci & Technol, Fac Chem, Dept Bioorgan Chem, Wroclaw, Poland; [Koziol, Agata; Lochynski, Stanislaw] Acad Physiotherapy Wroclaw, Inst Cosmetol, Wroclaw, Poland; [Szczepanik, Maryla] Nicolaus Copernicus Univ, Dept Invertebrate Zool, Torun, Poland; [Gabrys, Beata; Dancewicz, Katarzyna] Univ Zielona Gora, Fac Biol Sci, Dept Bot & Ecol, Zielona Gora, Poland in 2020.0, Cited 16.0. The Name is 1,1,1-Triethoxyethane. Through research, I have a further understanding and discovery of 78-39-7. COA of Formula: C8H18O3

Terpenoid derivatives, which contain a preserved carane system in their structure, exhibit a broad spectrum of biological activities. Among them, we can distinguish insecticides, structures with pharmacological application etc. In the presented paper, the substrate – (-)-cis-caran-trans-4-ol was transformed using the reactions of typical organic synthesis to obtain novel derivatives. Most importantly, bromolactone ((-)-(1R,4R,6S)-2′-(bromomethyl)-4,7,7-trimethylspiro[bicyclo[4.1.0]heptan-3,3′-furan]-5′(4’H)-one) with the preserved carane system was synthesized. This bromolactone was tested for antifeedant activity against the lesser mealworm, Alphitobius diaperinus Panzer, and peach potato aphid (Myzus persicae). In addition, its moderate antibacterial activity was observed against the Bacillus subtilis strain (with Minimal Inhibitory Concentration of 200 mu g/mL).

COA of Formula: C8H18O3. About 1,1,1-Triethoxyethane, If you have any questions, you can contact Koziol, A; Fratczak, J; Grela, E; Szczepanik, M; Gabrys, B; Dancewicz, K; Lochynski, S or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Computed Properties of C15H12O. Zhang, GF; Fan, QK; Zhao, YY; Ding, CR in [Zhang, Guofu; Fan, Qiankun; Zhao, Yiyong; Ding, Chengrong] Zhejiang Univ Technol, Coll Chem Engn, Hangzhou 310014, Zhejiang, Peoples R China published Copper-Promoted Oxidative Intramolecular C-H Amination of Hydrazones to Synthesize 1H-Indazoles and 1H-Pyrazoles Using a Cleavable Directing Group in 2019, Cited 72. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7.

A facile and efficient synthesis of 1H-indazoles and 1H-pyrazoles through a copper-promoted oxidative intramolecular C-H amination of hydrazones using a cleavable directing group was developed. This reaction is characterized by its mild conditions, operational simplicity, readily available reagents, and excellent yields. A tentative mechanism for Cu-mediated C-H oxidative amination was proposed.

About Chalcone, If you have any questions, you can contact Zhang, GF; Fan, QK; Zhao, YY; Ding, CR or concate me.. Product Details of 94-41-7

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

SDS of cas: 94-41-7. In 2021.0 MOL DIVERS published article about BIOLOGICAL EVALUATION; CHOLESTEROL; DRUG; ANTIOXIDANT; DERIVATIVES; EZETIMIBE; NIACIN in [Shoman, Mai E.; Abuo-Rahma, Gamal El-Din A.] Menia Univ, Fac Pharm, Dept Med Chem, Al Minya 61519, Egypt; [Aboelez, Moustafa O.] Sohag Univ, Fac Pharm, Dept Pharmaceut Chem, Sohag 82524, Egypt; [Shaykhon, Montaser Sh A.] Al Azhar Univ, Fac Pharm, Dept Pharmaceut Chem, Assiut 71524, Egypt; [Ahmed, Sanaa A.] Sohag Univ, Fac Med, Dept Pharmacol, Sohag 82524, Egypt; [Elhady, Omar M.] Sohag Univ, Dept Chem, Sohag 82524, Egypt in 2021.0, Cited 33.0. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7.

Nicotinic acid hydrazide was incorporated into new 4,5-dihydro-5-hydroxy-3,5-diphenylpyrazol-1-yl derivatives. Compounds 6a-h were synthesized, and their antihyperlipidemic activity was evaluated in high cholesterol diet-fed rat model. Compounds 6e, 6f were found to decrease the levels of serum total cholesterol by 14-19% compared to control group. Total triglycerides were also reduced by 24-28% and LDL cholesterol by 16%. As expected from parent niacin, compounds 6e and 6f caused an elevation of HDL cholesterol by 33-41%. Docking study supported the ability of designed compounds to block NPC1L1 active site in a manner similar to that observed with ezetimibe.

SDS of cas: 94-41-7. About Chalcone, If you have any questions, you can contact Shoman, ME; Aboelez, MO; Shaykhon, MSA; Ahmed, SA; Abuo-Rahma, GEA; Elhady, OM or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

HPLC of Formula: C8H18O3. In 2019.0 MOLECULES published article about LINE CACO-2; CAPSINOIDS; MECHANISMS; RECEPTOR in [Lieder, Barbara; Hans, Joachim; Hentschel, Fabia; Geissler, Katrin; Ley, Jakob] Symrise AG, Muehlenfeldstr 1, D-53479 Holzminden, Germany; [Lieder, Barbara] Univ Vienna, Dept Physiol Chem, CDL Taste Res, Althanstr 14, A-1090 Vienna, Austria in 2019.0, Cited 24.0. The Name is 1,1,1-Triethoxyethane. Through research, I have a further understanding and discovery of 78-39-7.

With raising prevalence of obesity, the regulation of human body fat is increasingly relevant. The modulation of fatty acid uptake by enterocytes represents a promising target for body weight maintenance. Recent results demonstrated that the trigeminal active compounds capsaicin, nonivamide, and trans-pellitorine dose-dependently reduce fatty acid uptake in differentiated Caco-2 cells as a model for the intestinal barrier. However, non-pungent alternatives have not been investigated and structural determinants for the modulation of intestinal fatty acid uptake have not been identified so far. Thus, based on the previous results, we synthesized 23 homovanillic acid esters in addition to the naturally occurring capsiate and screened them for their potential to reduce intestinal fatty acid uptake using the fluorescent fatty acid analog Bodipy-C12 in differentiated Caco-2 cells as an enterocyte model. Whereas pre-incubation with 100 mu M capsiate did not change fatty acid uptake by Caco-2 enterocytes, a maximum inhibition of -47% was reached using 100 mu M 1-methylpentyl-2-(4-hydroxy-3-methoxy-phenyl)acetate. Structural analysis of the 24 structural analogues tested in the present study revealed that a branched fatty acid side chain, independent of the chain length, is one of the most important structural motifs associated with inhibition of fatty acid uptake in Caco-2 enterocytes. The results of the present study may serve as an important basis for designing potent dietary inhibitors of fatty acid uptake.

HPLC of Formula: C8H18O3. About 1,1,1-Triethoxyethane, If you have any questions, you can contact Lieder, B; Hans, J; Hentschel, F; Geissler, K; Ley, J or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Recommanded Product: 78-39-7. Authors Huang, TW; Nagayama, M; Matsuda, J; Sasaki, K; Hayashi, A in MDPI published article about in [Huang, Ting-Wei; Sasaki, Kazunari; Hayashi, Akari] Kyushu Univ, Dept Hydrogen Energy Syst, Nishi Ku, 744 Motooka, Fukuoka 8190395, Japan; [Nagayama, Mayumi; Sasaki, Kazunari; Hayashi, Akari] Kyushu Univ, COI C2RSC, Nishi Ku, 744 Motooka, Fukuoka 8190395, Japan; [Matsuda, Junko; Sasaki, Kazunari; Hayashi, Akari] Kyushu Univ, Int Res Ctr Hydrogen Energy, Nishi Ku, 744 Motooka, Fukuoka 8190395, Japan; [Sasaki, Kazunari; Hayashi, Akari] Kyushu Univ, NEXT FC, Nishi Ku, 744 Motooka, Fukuoka 8190395, Japan; [Hayashi, Akari] Kyushu Univ, Q PIT, Nishi Ku, 744 Motooka, Fukuoka 8190395, Japan in 2021.0, Cited 38.0. The Name is 1,1,1-Triethoxyethane. Through research, I have a further understanding and discovery of 78-39-7

To improve the properties of mesoporous carbon (MC), used as a catalyst support within electrodes, MC fibers (MCFs) were successfully synthesized by combining organic-organic self-assembly and electrospinning deposition and optimizing heat treatment conditions. The pore structure was controlled by varying the experimental conditions. Among MCFs, MCF-A, which was made in the most acidic condition, resulted in the largest pore diameter (4-5 nm), and the porous structure and carbonization degree were further optimized by adjusting heat treatment conditions. Then, since the fiber structure is expected to have an advantage when MCFs are applied to devices, MCF-A layers were prepared by spray printing. For the resistance to compression, MCF-A layers showed higher resistance (5.5% change in thickness) than the bulk MC layer (12.8% change in thickness). The through-plane resistance was lower when the fiber structure remained more within the thin layer, for example, +8 m omega for 450 rpm milled MCF-A and +12 m omega for 800 rpm milled MCF-A against the gas diffusion layer (GDL) 25BC carbon paper without a carbon layer coating. The additional advantages of MCF-A compared with bulk MC demonstrate that MCF-A has the potential to be used as a catalyst support within electrodes in energy devices.

Recommanded Product: 78-39-7. About 1,1,1-Triethoxyethane, If you have any questions, you can contact Huang, TW; Nagayama, M; Matsuda, J; Sasaki, K; Hayashi, A or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Safety of 1,1,1-Triethoxyethane. In 2020.0 RUSS J ORG CHEM+ published article about BIOLOGICAL EVALUATION; DERIVATIVES in [Paronikyan, E. G.; Dashyan, Sh. Sh.; Mamyan, S. S.] Natl Acad Sci Armenia, Sci & Technol Ctr Organ & Pharmaceut Chem, Yerevan 0014, Armenia in 2020.0, Cited 10.0. The Name is 1,1,1-Triethoxyethane. Through research, I have a further understanding and discovery of 78-39-7.

A method for the synthesis of derivatives of 8-hydrazino 6-thioxopyrano[3,4-c]pyridine has been developed. Derivatives of 8-hydrazino-6-(methylsulfanyl)pyrano[3,4-c]pyridines and 5-(or 3)-(alkylsulfanyl)pyrano[3,4-c][1,2,4]triazolo[4,3-a]pyridines have been synthesized. The thione-thiol tautomerism of 5-thioxopyrano[3,4-c][1,2,4]triazolo[4,3-a]pyridine has been studied. In a basic medium, the equilibrium shifts toward the thiol form, which has allowed synthesis ofS-alkyl-substituted triazolo[4,3-a]pyridines.

About 1,1,1-Triethoxyethane, If you have any questions, you can contact Paronikyan, EG; Dashyan, SS; Mamyan, SS or concate me.. Name: 1,1,1-Triethoxyethane

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

An article New nicotinic acid-based 3,5-diphenylpyrazoles: design, synthesis and antihyperlipidemic activity with potential NPC1L1 inhibitory activity WOS:000516253300001 published article about BIOLOGICAL EVALUATION; CHOLESTEROL; DRUG; ANTIOXIDANT; DERIVATIVES; EZETIMIBE; NIACIN in [Shoman, Mai E.; Abuo-Rahma, Gamal El-Din A.] Menia Univ, Fac Pharm, Dept Med Chem, Al Minya 61519, Egypt; [Aboelez, Moustafa O.] Sohag Univ, Fac Pharm, Dept Pharmaceut Chem, Sohag 82524, Egypt; [Shaykhon, Montaser Sh A.] Al Azhar Univ, Fac Pharm, Dept Pharmaceut Chem, Assiut 71524, Egypt; [Ahmed, Sanaa A.] Sohag Univ, Fac Med, Dept Pharmacol, Sohag 82524, Egypt; [Elhady, Omar M.] Sohag Univ, Dept Chem, Sohag 82524, Egypt in 2021.0, Cited 33.0. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7. Computed Properties of C15H12O

Nicotinic acid hydrazide was incorporated into new 4,5-dihydro-5-hydroxy-3,5-diphenylpyrazol-1-yl derivatives. Compounds 6a-h were synthesized, and their antihyperlipidemic activity was evaluated in high cholesterol diet-fed rat model. Compounds 6e, 6f were found to decrease the levels of serum total cholesterol by 14-19% compared to control group. Total triglycerides were also reduced by 24-28% and LDL cholesterol by 16%. As expected from parent niacin, compounds 6e and 6f caused an elevation of HDL cholesterol by 33-41%. Docking study supported the ability of designed compounds to block NPC1L1 active site in a manner similar to that observed with ezetimibe.

About Chalcone, If you have any questions, you can contact Shoman, ME; Aboelez, MO; Shaykhon, MSA; Ahmed, SA; Abuo-Rahma, GEA; Elhady, OM or concate me.. Recommanded Product: 94-41-7

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

In 2020 FUTURE MED CHEM published article about BIOLOGICAL EVALUATION; ANTIHYPERGLYCEMIC EVALUATION; PYRAZOLINE DERIVATIVES; ANTIOXIDANT; BEARING; DESIGN; CANCER; MOIETY; ANTIBACTERIAL; IMIDAZOLE in [Chouiter, Mohamed, I; Boulebd, Houssem; Belfaitah, Ali] Univ Freres Mentouri Constantine, Fac Sci Exactes, Lab Prod Nat Origine Vegetale & Synthese Organ, Campus Chaabat Ersas, Constantine 25000, Algeria; [Pereira, David M.; Valentao, Patricia; Andrade, Paula B.] Univ Porto, Fac Farm, REQUIMTE LAQV, Lab Farmacognosia,Dept Quim, R Jorge Viterbo Ferreira 228, P-4050313 Porto, Portugal; [Silva, Artur M. S.] Univ Aveiro, QOPNA, P-3810193 Aveiro, Portugal; [Silva, Artur M. S.] Univ Aveiro, LAQV REQUIMTE, Dept Chem, P-3810193 Aveiro, Portugal in 2020, Cited 61. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7. Name: Chalcone

Aim: There is a continuous and urgent need for new anticancer agents with novel structures and target selectivity. Methods & results: The anticancer activity of the prepared compounds was assessed against human lung (A549) and stomach (AGS) cancer cell lines and evaluated in the noncancer human lung fibroblast (MRC-5) cell line. 2-Pyrazolines were devoid of toxicity in all cell lines used, chalcones bearing a beta-(benz)imidazole moiety being toxic toward AGS cell line. Mechanistic studies showed that these compounds trigger loss of cell viability and mitochondrial membrane potential, while eliciting morphological traits compatible with regulated cell death, which was ultimately shown to derive from caspase activation, specifically caspase-3. Conclusion: Chalcones 1-3 have been identified as new and promising anticancer agents toward the AGS cell line.

About Chalcone, If you have any questions, you can contact Chouiter, MI; Boulebd, H; Pereira, DM; Valentao, P; Andrade, PB; Belfaitah, A; Silva, AMS or concate me.. Computed Properties of C15H12O

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Product Details of 94-41-7. I found the field of Chemistry very interesting. Saw the article Generalized Chemoselective Transfer Hydrogenation/Hydrodeuteration published in 2020, Reprint Addresses Cui, XL; Wu, YJ (corresponding author), Zhengzhou Univ, Key Lab Appl Chem Henan Univ, Green Catalysis Ctr, Henan Key Lab Chem Biol & Organ Chem, Zhengzhou 450052, Peoples R China.; Cui, XL; Wu, YJ (corresponding author), Zhengzhou Univ, Coll Chem, Zhengzhou 450052, Peoples R China.. The CAS is 94-41-7. Through research, I have a further understanding and discovery of Chalcone.

A generalized, simple and efficient transfer hydrogenation of unsaturated bonds has been developed using HBP in and various proton reagents as hydrogen sources. The substrates, including alkenes, alkynes, aromatic heterocycles, aldehydes, ketones, imines, azo, nitro, epoxy and nitrile compounds, are all applied to this catalytic system. Various groups, which cannot survive under the Pd/C/H-2 combination, are tolerated. The activity of the reactants was studied and the trends are as follows:styrene>diphenylmethanimine>benzaldehyde>azobenzene>nitrobenzene>quinoline>acetophenone>benzonitrile. Substrates bearing two or more different unsaturated bonds were also investigated and transfer hydrogenation occurred with excellent chemoselectivity. Nano-palladium catalystin situgenerated from Pd(OAc)(2) and HBP in extremely improved the TH efficiency. Furthermore, chemoselective anti-Markovnikov hydrodeuteration of terminal aromatic olefins was achieved using D2O and HBP in via in situ HD generation and discrimination.

Product Details of 94-41-7. About Chalcone, If you have any questions, you can contact Wang, Y; Cao, XY; Zhao, LY; Pi, C; Ji, JF; Cui, XL; Wu, YJ or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com