The important role of Thiazolidin-2-one

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Synthetic Route of 2682-49-7, One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time.In a article, authors is Ulusoy Guezeldemirci, Nuray, mentioned the application of Synthetic Route of 2682-49-7, Name is Thiazolidin-2-one, molecular formula is C3H5NOS

Synthesis and antiviral activity evaluation of new 4-thiazolidinones bearing an imidazo[2,1-b]thiazole moiety

A series of new 4-thiazolidinone derivatives were synthesized and evaluated against diverse DNA- and RNA-viruses in mammalian cell cultures. Some of the compounds were found to exhibit moderate antiviral activity. 3-Propyl-2-[((6-(4-chlorophenyl)imidazo[2,1-b]thiazol-3-yl)acetyl)hydrazono]-5-methyl-4-thiazolidinone 13, displayed modest yet consistent activity against three strains of influenza A virus, including the 2009 pandemic virus A/H1N1 Virginia/ATCC3/2009 (cytotoxicity >100 muM). Compounds 6 and 11 displayed activity against vesicular stomatitis virus in HeLa cells (antiviral EC50 values of 9 (cytotoxicity 100 muM) and 2 muM (cytotoxicity 20 muM), respectively). Neither of the compounds was active against HIV.

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Reference£º
Quinuclidine – Wikipedia,
Quinuclidine | C7H473N | ChemSpider