New Advances in Chemical Research, May 2021. Application of 1055361-35-7, Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction by binding to a specific portion of an enzyme and thus slowing or preventing a reaction from occurring. In a document type is Article, and a compound is mentioned, 1055361-35-7, 4-(4-((2,4-Dioxothiazolidin-5-ylidene)methyl)-2-methoxyphenoxy)-3-(trifluoromethyl)benzonitrile, introducing its new discovery.
The 3JCH couplings at bridgehead carbons in naphthalene and quinoline derivatives have been classified as “through” ring and “cross” ring interactions.Further divisions of the couplings have been introduced in an attempt to rationalize the interactions such that they may be used for structural assignments.The influence of central ?-bond order and of the heterocyclic nitrogen atom on the couplings has been discussed.From a study of the 3J couplings at C-9 and C-10 in 45 quinoline derivatives the coupling constant ranges observed were “through” ring (via 9,10-bond): J94 4.9-6.1 Hz, J95 5.5-7.3 Hz, J10.8 4.1-5.3 Hz; “cross” ring: J92 11.0-13.5 Hz, J97 6.7-9.8 Hz, J10.3 4.4-7.3 Hz, J10.6 5.2-9.1 Hz.
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Reference：
Quinuclidine – Wikipedia,
Quinuclidine | C7H917N | ChemSpider