I found the field of Chemistry very interesting. Saw the article Synthesis of Various Derivatives of [1,3]Selenazolo[4,5-d]pyrimidine and Exploitation of These Heterocyclic Systems as Antibacterial, Antifungal, and Anticancer Agents published in 2020.0. Recommanded Product: 78-39-7, Reprint Addresses Shiri, A (corresponding author), Ferdowsi Univ Mashhad, Fac Sci, Dept Chem, Mashhad, Razavi Khorasan, Iran.. The CAS is 78-39-7. Through research, I have a further understanding and discovery of 1,1,1-Triethoxyethane
A number of diversely functionalized derivatives of a novel [1,3]selenazolo[4,5-d]pyrimidine have been synthesized through heterocyclization of some 2,4,5-trisubstituted-1,3-selenazoles with orthoesters in refluxing acetic acid. The synthetic compounds were evaluated for their antimicrobial activity against a panel of microorganisms including Gram-negative bacteria, Gram-positive bacteria, and pathogenic fungi. The antifungal results revealed that the new selenium-containing heterocycles were as good as or sometimes better than terbinafine and fluconazole. The in vitro anticancer activities of aforementioned heterocyclic compounds were screened against human breast carcinoma MCF-7 and HeLa cervical cancer cells as well as HDF (human dermal fibroblast) normal cells. Antiproliferative results indicated that compounds with piperidine moiety on MCF-7 cells and with morpholine moiety on HeLa cells exhibited well broad-spectrum of anticancer activities with 397, 298 and 235 mu M and 533, 390 and 204 mu M of IC(50)values after 24, 48 and 72 h of treatments, respectively, while they had no significant toxic effects on normal cells.
Recommanded Product: 78-39-7. Welcome to talk about 78-39-7, If you have any questions, you can contact Sheikhi-Mohammareh, S; Shiri, A; Maleki, EH; Matin, MM; Beyzaei, H; Baranipour, P; Oroojalian, F; Memariani, T or send Email.
Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com