I found the field of Chemistry very interesting. Saw the article Catalytic asymmetric cycloaddition of unsymmetrical EWG-activated alkenes to fully substituted pyrrolidines bearing three different carbonyl groups published in 2019.0. Application In Synthesis of Chalcone, Reprint Addresses Li, L; Xu, LW (corresponding author), Hangzhou Normal Univ, Key Lab Organosilicon Chem & Mat Technol, Key Lab Organosilicon Mat Technol Zhejiang Prov, Minist Educ,Coll Mat Chem & Chem Engn, Hangzhou 311121, Zhejiang, Peoples R China.; Xu, LW (corresponding author), Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Beijing, Peoples R China.; Xu, LW (corresponding author), Univ Chinese Acad Sci, Beijing, Peoples R China.. The CAS is 94-41-7. Through research, I have a further understanding and discovery of Chalcone
A unique 1,3-dipolar [3+2] cycloaddition of alkyl 4-oxo-4-arylbut-2-enoates bearing two different electron-withdrawing groups was completed by using the silver/(R)-DTBM-Segphos catalyst system, which gives the corresponding fully substituted pyrrolidines with four stereogenic centers in good yields and with excellent enantioselectivities (up to 98% ee).
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Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com