Quality Control of Chalcone. Recently I am researching about TETRONIC ACID-DERIVATIVES; ALPHA,BETA-UNSATURATED KETONES; CONJUGATE ADDITION; BETA-KETOCARBONYLS; ALKYLATION; 3(2H)-FURANONES; CONSTRUCTION; QUATERNARY; CATALYSIS; ALDEHYDES, Saw an article supported by the Guangzhou University of Chinese Medicine. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Huang, HC; Lu, X; Mao, YK; Ye, JX. The CAS is 94-41-7. Through research, I have a further understanding and discovery of Chalcone
The asymmetric Michael reaction of 3(2H) furanones and alpha, beta-unsaturated ketones was investigated, with the employment of a bulky chiral primary amine. The protocol afforded a series of substituted furanone derivatives in a highly diastereo-(> 30 : 1 dr) and enantioselective (up to 93% ee) manner with generally good to excellent yields (up to 99%).
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Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com