Teja, C; Babu, SN; Noor, A; Daniel, JA; Devi, SA; Khan, FR in [Teja, Chitrala; Khan, Fazlur Rahman] Vellore Inst Technol, Sch Adv Sci, Dept Chem, Organ & Med Chem Res Lab, Vellore 632014, Tamil Nadu, India; [Babu, Spoorthy N.; Noor, Ayesha] Vellore Inst Technol, Ctr Bio Separat Technol, Vellore 632014, Tamil Nadu, India; [Daniel, J. Arul; Devi, S. Asha] Vellore Inst Technol, Sch Biosci & Technol, Dept Biomed Sci, Vellore 632014, Tamil Nadu, India published Cu/TEMPO catalyzed dehydrogenative 1,3-dipolar cycloaddition in the synthesis of spirooxindoles as potential antidiabetic agents in 2020.0, Cited 77.0. Computed Properties of C15H12O. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7.
A series of spiro-[indoline-3,3 ‘-pyrrolizin/pyrrolidin]-2-ones, 4, 5 and 6 were synthesized in a sequential manner from Cu-TEMPO catalyzed dehydrogenation of alkylated ketones, 1 followed by 1,3-dipolar cycloaddition of azomethine ylides via decarboxylative condensation of isatin, 2 and l-proline/sarcosine, 3 in high regioselectivities and yields. The detailed mechanistic studies were performed to identify the reaction intermediates, which revealed that the reaction proceeds via dehydrogenative cycloaddition. Additionally, the regio and stereochemistry of the synthesized derivatives were affirmed by 2D NMR spectroscopic studies. The synthesized derivatives were explored further with molecular docking, in vitro antioxidant, and anti-diabetic activities.
Computed Properties of C15H12O. Welcome to talk about 94-41-7, If you have any questions, you can contact Teja, C; Babu, SN; Noor, A; Daniel, JA; Devi, SA; Khan, FR or send Email.
Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com