Related Products of 2682-49-7, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 2682-49-7, Thiazolidin-2-one, introducing its new discovery.
Synthesis and pharmacological evaluation of some 2-(4-isobutylphenyl)-N-(4-oxo-2-arylthiazolidin-3-yl) propanamides
Some derivatives of ibuprofen bearing 4H-thiazolidin-4-one moiety were synthesized from ibuprofen and studied for their pharmacological activities. Methyl ester of ibuprofen I was synthesized from ibuprofen and then converted to hydrazide II with the reaction of hydrazine hydrate. Hydrazide of ibuprofen then reacted with aromatic aldehydes in the presence of glacial acetic acid to yield the hydrazones III which on reaction with thioglycolic acid and dimethyl formamide in presence of catalytic amount of anhydrous zinc chloride furnished the title compounds IV. The structures of synthesized compounds were elucidated mainly by spectral evidence. All the synthesized title compounds were screened for their anti-inflammatory activity. Title compounds were also studied for their ulcerogenic potential. The compounds exhibited moderate to significant activities.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Related Products of 2682-49-7. In my other articles, you can also check out more blogs about 2682-49-7
Reference£º
Quinuclidine – Wikipedia,
Quinuclidine | C7H300N | ChemSpider