Synthetic Route of 2682-49-7, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.2682-49-7, Name is Thiazolidin-2-one, molecular formula is C3H5NOS. In a article£¬once mentioned of 2682-49-7
Microwave assisted one pot synthesis of some 2-(substituted) phenyl-3-pyridin-2-yl-1,3-thiazolidin-4-ones under solvent free conditions
We have reported an efficient, operationally simple, environmental benign one pot synthesis of Some 2-(Substituted) Phenyl-3-Pyridin-2-yl-1,3-Thiazolidin-4-Ones Under Solvent Free Conditions (a-f) by a mixture of equimolar quantities of 2-amino pyridine, substituted benzaldehyde and thioglycolic acid with a pinch of anhydrous zinc chloride was heated in a microwave oven for 10-15 min. The progress of the reaction was monitored by TLC. The yields were in the range of 61-86 %. Synthesized compounds were screened for antimicrobial activities against E. coli as Gram negative bacteria and S. aureus as Gram positive bacteria. Some of the compounds displayed pronounced biological activity. The structures of synthesized compounds were elucidated on the basis of spectral (1H NMR,!3 C NMR and IR) and elemental analysis.
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Reference£º
Quinuclidine – Wikipedia,
Quinuclidine | C7H334N | ChemSpider