Category: 94-41-7

Safety of Chalcone. In 2019.0 ASIAN J ORG CHEM published article about ASYMMETRIC TRANSFER HYDROGENATION; IRIDIUM-CATALYZED ALKYLATION; EFFICIENT; COMPLEX; AMINES; AUTOTRANSFER; REDUCTION; STRATEGY in [Ibrahim, Jessica Juweriah; Reddy, C. Bal; Zhang, Shaochun; Yang, Yong] Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Qingdao 266101, Shandong, Peoples R China; [Ibrahim, Jessica Juweriah] Univ Chinese Acad Sci, Beijing 100049, Peoples R China in 2019.0, Cited 52.0. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7.

In this study, we present a facile, cost-effective and expedient hydrogen-borrowing strategy to perform alpha-alkylation of ketones with primary alcohols using FeCl2 as the catalyst. A set of both ketones and alcohols could be efficiently alkylated to produce their corresponding ketones in good to high yields.

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Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

In 2019.0 INT J BIOL MACROMOL published article about NANOPARTICLES; N-2-ARYL-SUBSTITUTED-1,2,3-TRIAZOLES; PYRIMIDINE; CHALCONES; CATALYST; COMPLEX; HPLC in [Khalil, Khaled D.] Taibah Univ, Dept Chem, Fac Sci, Yanbu 46423, Saudi Arabia; [Riyadh, Sayed M.; Ali, Imran] Taibah Univ, Dept Chem, Fac Sci, Al Madinah Al Munawarah 30002, Saudi Arabia; [Khalil, Khaled D.; Riyadh, Sayed M.; Gomha, Sobhi M.] Cairo Univ, Dept Chem, Fac Sci, Giza 12613, Egypt; [Gomha, Sobhi M.] Islamic Univ Almadinah Almonawara, Fac Sci, Dept Chem, Almadinah Almonawara 42351, Saudi Arabia; [Ali, Imran] Cent Univ, Jamia Millia Islamia, Dept Chem, New Delhi, India in 2019.0, Cited 44.0. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7. SDS of cas: 94-41-7

Chitosan copper (II) oxide nanocomposite was synthesized, characterized and used to synthesize [1,2,3] triazoles. Nanocomposite was characterized by using FTIR, XRD, FESEM, and EDS techniques, which reflected rough morphology. The powerful catalytic activity of hybrid nanocomposite was utilized to synthesize chalcones (3a-p) in relatively high yields (82%-98%) and multicomponent regio-selective cycloaddition of chalones, aryl halides (4), and sodium azide to afford the expected N-2-aryl[1,2,3]triazoles (5a-h) (80%-95% yield) rather than N-1-aryl(1,2,3]-triazoles (6a-h). The performance of nanomaterial was optimized by several variables. The capability of the nanocomposite was compared with previous work and the nanocomposite was found more efficient, economic and reproducible. The hybrid nanocomposite could be easily isolated form the reaction mixture and recycled four times without any significant loss of its catalytic activity. The reported catalyst is an inexpensive for good yields of the triazoles and may be used at industrial production for the reported compounds. (C) 2019 Published by Elsevier B.V.

SDS of cas: 94-41-7. About Chalcone, If you have any questions, you can contact Khalil, KD; Riyadh, SM; Gomha, SM; Ali, I or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

An article Water hyacinth ash: an efficient green catalyst for the synthesis of beta-amino carbonyl/nitrile compounds by aza-Michael reaction at room temperature WOS:000532826500087 published article about BIODIESEL PRODUCTION; PALLADIUM NANOPARTICLES; CONVENIENT SYNTHESIS; CONJUGATE ADDITION; EXTRACT; SOLVENT; BASE; ACID; OIL; NITRATE in [Talukdar, Anjumani; Deka, Dibakar Chandra] Gauhati Univ, Dept Chem, Gauhati 781014, Assam, India; [Deka, Dibakar Chandra] Mahabdev Univ, PO Dikrong, Narayanpur 784164, Assam, India in 2020.0, Cited 44.0. Name: Chalcone. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7

Water hyacinth ash is found to be an efficient and reusable catalyst for the synthesis of beta-amino carbonyl/nitrile compounds by aza-Michael reaction of amines with alpha,beta-unsaturated compounds at room temperature under solvent free condition. Due to low cost of the catalyst, good activity, ease of handling and easy recovery with high yields of the products in short reaction time, easy workup procedure, mild reaction condition, the protocol is highly applicable in synthetic organic chemistry.

Name: Chalcone. Bye, fridends, I hope you can learn more about C15H12O, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Category: thiazolidines. In 2021 CHEMSUSCHEM published article about DEPENDENT AMINE OXIDASES; AEROBIC OXIDATION; CATALYTIC MECHANISM; ALCOHOL OXIDATION; TOPA QUINONE; ACTIVE-SITE; COPPER; HYDROGEN; MODEL; PYRIMIDINES in [K. Bains, Amreen; Adhikari, Debashis] Indian Inst Sci Educ & Res IISER Mohali, Dept Chem Sci, Sas Nagar 140306, Punjab, India; [Ankit, Yadav] Indian Inst Sci Educ & Res IISER Mohali, Dept Earth & Environm Sci, Sas Nagar 140306, Punjab, India in 2021, Cited 42. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7.

A redox-active iminoquinone motif connected with pi-delocalized pyrene core has been reported that can perform efficient two-electron oxidation of a class of substrates. The design of the molecule was inspired by the organic redox cofactor topaquinone (TPQ), which executes amine oxidation in the enzyme, copper amine oxidase. Easy oxidation of both primary and secondary alcohols happened in the presence of catalytic KOtBu, which could reduce the ligand backbone to its iminosemiquinonate form under photoinduced conditions. Moreover, this easy oxidation of alcohols under aerobic condition could be elegantly extended to multi-component, one-pot coupling for the synthesis of quinoline and pyrimidine. This organocatalytic approach is very mild (70 degrees C, 8 h) compared to a multitude of transition-metal catalysts that have been used to prepare these heterocycles. A detailed mechanistic study proves the intermediacy of the iminosemiquinonate-type radical and a critical hydrogen atom transfer step to be involved in the dehydrogenation reaction.

Category: thiazolidines. Welcome to talk about 94-41-7, If you have any questions, you can contact Bains, AK; Ankit, Y; Adhikari, D or send Email.

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Recently I am researching about ONE-POT SYNTHESIS; REGIOSELECTIVE SYNTHESIS; EFFICIENT SYNTHESIS; 1,3-DIPOLAR CYCLOADDITION; SUBSTITUTED PYRAZOLES; CATALYZED SYNTHESIS; DIAZO-COMPOUNDS; ACID-CHLORIDES; HYDRAZINES; INDAZOLES, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [20702051]; Natural Science Foundation of Zhejiang ProvinceNatural Science Foundation of Zhejiang Province [LY13B020017]. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Zhang, GF; Fan, QK; Zhao, YY; Ding, CR. The CAS is 94-41-7. Through research, I have a further understanding and discovery of Chalcone. Formula: C15H12O

A facile and efficient synthesis of 1H-indazoles and 1H-pyrazoles through a copper-promoted oxidative intramolecular C-H amination of hydrazones using a cleavable directing group was developed. This reaction is characterized by its mild conditions, operational simplicity, readily available reagents, and excellent yields. A tentative mechanism for Cu-mediated C-H oxidative amination was proposed.

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Name: Chalcone. Zhang, ZY; Miao, YR; Xu, M; Cheng, WM; Yang, CY; She, XJ; Geng, QQ; Zhang, QL in [Zhang, Zhiyong; Miao, Yiru; Xu, Min; Cheng, Wenming; Yang, Chuanyan; She, Xiangjian; Geng, Qianqian; Zhang, Qunlin] Anhui Med Univ, Sch Pharm, Hefei 230032, Anhui, Peoples R China published TianJiu therapy for alpha-naphthyl isothiocyanate-induced intrahepatic cholestasis in rats treated with fresh Ranunculus sceleratus L. in 2020.0, Cited 54.0. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7.

Ethnopharmacological relevance: TianJiu (TJ) therapy, one type of cold moxibustion, applies to specific acupuncture points with herbal patches of hot nature, providing a constant irritant to the skin until the presence of hyperemia and blistering. Traditional and clinical reports suggest that TJ is an effective therapy for the treatment of jaundice with fresh Ranunculus sceleratus L. (RS), in which protoanemonin is one of the main irritant constituents. However, the therapeutic effect of TJ treatment with fresh RS against intrahepatic cholestasis has not been studied in animal experiments. Aim of the study: Present study was undertaken to investigate the effect of TJ treatment with fresh RS against intrahepatic cholestasis in rats and provide an experimental basis for the underlying mechanism of TJ therapy. Materials and methods: Male intrahepatic cholestatic Sprague-Dawley rats induced by 2% alpha-naphthylisothiocyanate (ANIT, 80 mg/kg B.W.) were treated by TJ therapy with fresh RS. The levels of serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), direct bilirubin (DBIL), total bilirubin (TBIL), total bile acid (TBA), hepatic malondialdehyde (MDA) and nitric monoxide (NO), as well as hepatic body ratio, bile flow and hepatic histopathological assay were measured and evaluated to investigate the therapeutic effect of TJ treatment with fresh RS. Phytochemical analysis of fresh and dried RS was performed by gas chromatography-mass spectrometer (GC-MS). Results: After TJ treatment with fresh RS, the abnormally elevated levels of serum AST, ALT, ALP, DBIL, TBIL and TBA, as well as hepatic MDA and NO at 108 h were reduced significantly (versus model group, P < 0.01). The hepatic body ratio, bile flow and hepatic pathological change of cholestatic rats at 108 h in TJ group were restored when compared with those of model group. Thirty-one compounds including lactones, flavonoids and phenolic acids were identified and determined by GC-MS analysis. The content of protoanemonin in fresh RS (9.49%) was about 25-fold higher than that in dried RS (0.38%). Conclusions: TJ treatment with fresh RS exhibited good therapeutic effect on ANIT-induced intrahepatic cholestasis in rats, which may be due to the attenuated oxidative stress in the liver tissue. It is rational for the ancients to choose fresh RS as TJ herbal patches because of its abundant protoanemonin with the character of irritant. The qualitative and quantitative results of GC-MS analysis provided the chemical basis of TJ therapy with fresh RS, which can be regarded as a simple and efficient method for the treatment of cholestasis hepatitis. Name: Chalcone. Welcome to talk about 94-41-7, If you have any questions, you can contact Zhang, ZY; Miao, YR; Xu, M; Cheng, WM; Yang, CY; She, XJ; Geng, QQ; Zhang, QL or send Email.

Reference:
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,Thiazolidine – ScienceDirect.com

Computed Properties of C15H12O. Recently I am researching about HIGHLY SUBSTITUTED PYRIDINES; THIYL-RADICAL CATALYST; ONE-POT SYNTHESIS; VINYL AZIRIDINES; STEREOSELECTIVE-SYNTHESIS; SYMMETRICAL PYRIDINES; KETOXIME ACETATES; RECENT PROGRESS; OXIME ACETATES; CYCLIZATION, Saw an article supported by the start-up funds of Huanghe Scholars Program from Henan University – China Postdoctoral Science Foundation [2020M672199, 2019M662477]; Natural Science Foundation of Henan [202300410062]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [U1704176]; Young Talents Program of Medical School of Henan University [2019005]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Liu, YT; Luo, W; Wang, ZJ; Zhao, YX; Zhao, JJ; Xu, XJ; Wang, CJ; Li, P. The CAS is 94-41-7. Through research, I have a further understanding and discovery of Chalcone

A visible-light photoredox-catalyzed formal [5 + 1] cycloaddition of N-tosyl vinylaziridines with difluoroalkyl halides as unique C1 synthons was developed. The procedure provides an efficient and practical method to synthesize diverse pyridines in moderate to good yields. The reaction underwent a radical-initiated kinetically controlled ring-opening of vinylaziridines and involved a key alpha,beta-unsaturated imine intermediate, followed by an E2 elimination, a 6 pi electrocyclization, and defluorinated aromatization.

Computed Properties of C15H12O. About Chalcone, If you have any questions, you can contact Liu, YT; Luo, W; Wang, ZJ; Zhao, YX; Zhao, JJ; Xu, XJ; Wang, CJ; Li, P or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Recently I am researching about ANTIBACTERIAL ACTIVITY; ORGANOCATALYTIC ACTIVATION; BLIGHT, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21772029, 21801051]; National Key Technologies R Program [2014BAD23B01]; Guizhou Province Returned Oversea Student Science and Technology Activity Program [(2014)-2]; Science and Technology Department of Guizhou Province [[2018]2802, [2019]1020]; Guizhou University; Guizhou Province First-Class Disciplines Project (Yiliu Xueke Jianshe Xiangmu) [GNYL(2017) 008]; Singapore National Research FoundationNational Research Foundation, Singapore [NRF-NRFI2016-06]; Ministry of Education of SingaporeMinistry of Education, Singapore [MOE2013-T2-2-003, MOE2016-T2-1-032, RG108/16]; A*STAR Individual Research Grant [A1783c0008]; Nanyang Technological UniversityNanyang Technological University; The 10 Talent Plan (Shicengci) of Guizhou Province [[2016] 5649]; Nanyang Research Award Grant; Guizhou University of Traditional Chinese Medicine (China) [QMYY [2017]101]. Computed Properties of C15H12O. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Pan, DW; Mou, CL; Zan, NN; Lv, Y; Song, BA; Chi, YR; Jin, ZC. The CAS is 94-41-7. Through research, I have a further understanding and discovery of Chalcone

A chemoselective cascade cycloaddition reaction is developed for green and efficient access to cyclopenta-[c]pyridine derivatives. Simple and inexpensive NaOH is used as the sole catalyst for this process. The delta-carbon of cyclopropyl ester is activated as a nucleophiic carbon to initiate highly chemoselective cascade reactions. Cyclopenta-[c]pyridines bearing various substituents are afforded in excellent yields. Preliminary studies on the bioactivities of the afforded products show promising antibacterial activities for potential applications in plant protections.

Computed Properties of C15H12O. Welcome to talk about 94-41-7, If you have any questions, you can contact Pan, DW; Mou, CL; Zan, NN; Lv, Y; Song, BA; Chi, YR; Jin, ZC or send Email.

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In 2021.0 MOL DIVERS published article about BIOLOGICAL EVALUATION; CHOLESTEROL; DRUG; ANTIOXIDANT; DERIVATIVES; EZETIMIBE; NIACIN in [Shoman, Mai E.; Abuo-Rahma, Gamal El-Din A.] Menia Univ, Fac Pharm, Dept Med Chem, Al Minya 61519, Egypt; [Aboelez, Moustafa O.] Sohag Univ, Fac Pharm, Dept Pharmaceut Chem, Sohag 82524, Egypt; [Shaykhon, Montaser Sh A.] Al Azhar Univ, Fac Pharm, Dept Pharmaceut Chem, Assiut 71524, Egypt; [Ahmed, Sanaa A.] Sohag Univ, Fac Med, Dept Pharmacol, Sohag 82524, Egypt; [Elhady, Omar M.] Sohag Univ, Dept Chem, Sohag 82524, Egypt in 2021.0, Cited 33.0. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7. Safety of Chalcone

Nicotinic acid hydrazide was incorporated into new 4,5-dihydro-5-hydroxy-3,5-diphenylpyrazol-1-yl derivatives. Compounds 6a-h were synthesized, and their antihyperlipidemic activity was evaluated in high cholesterol diet-fed rat model. Compounds 6e, 6f were found to decrease the levels of serum total cholesterol by 14-19% compared to control group. Total triglycerides were also reduced by 24-28% and LDL cholesterol by 16%. As expected from parent niacin, compounds 6e and 6f caused an elevation of HDL cholesterol by 33-41%. Docking study supported the ability of designed compounds to block NPC1L1 active site in a manner similar to that observed with ezetimibe.

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Recommanded Product: Chalcone. In 2020.0 ACS CATAL published article about ALPHA,BETA-UNSATURATED CARBONYL; GOLD NANOPARTICLES; DEHYDROGENATION; PALLADIUM; OXIDATION; ALDEHYDES; COMBUSTION; AU/CEO2; ENONES; ESTERS in [Takei, Daisuke; Yatabe, Takafumi; Yabe, Tomohiro; Mizuno, Noritaka; Yamaguchi, Kazuya] Univ Tokyo, Dept Appl Chem, Sch Engn, Bunkyo Ku, Tokyo 1138656, Japan; [Jin, Xiongjie] Univ Tokyo, Dept Chem & Biotechnol, Sch Engn, Bunkyo Ku, Tokyo 1138656, Japan in 2020.0, Cited 57.0. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7.

Direct selective desaturation of carbonyl compounds to synthesize alpha,beta-unsaturated carbonyl compounds represents an environmentally benign alternative to classical stepwise procedures. In this study, we designed an ideal CeO2-supported Pd(II)-on-Au nanoparticle catalyst (Pd/Au/CeO2) and successfully achieved heterogeneously catalyzed selective desaturation of cyclohexanones to cyclohexenones using O-2 in air as the oxidant. Besides cyclohexenones, various bioactive enones can also be synthesized from the corresponding saturated ketones under open air conditions in the presence of Pd/Au/CeO2. Preliminary mechanistic studies revealed that alpha-C-H bond cleavage in the substrates is the turnoverlimiting step of this desaturation reaction.

Recommanded Product: Chalcone. Welcome to talk about 94-41-7, If you have any questions, you can contact Takei, D; Yatabe, T; Jin, XJ; Yabe, T; Mizuno, N; Yamaguchi, K or send Email.

Reference:
Thiazolidine – Wikipedia,
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