I found the field of Chemistry very interesting. Saw the article An Efficient Synthesis of the Pentasaccharide Repeating Unit of Pseudomonas aeruginosa Psl Exopolysaccharide published in 2020.0. Application In Synthesis of 1,1,1-Triethoxyethane, Reprint Addresses Borbas, A; Herczeg, M (corresponding author), Univ Debrecen, Dept Pharmaceut Chem, Egyet Ter 1, H-4032 Debrecen, Hungary.; Herczeg, M (corresponding author), Univ Debrecen, Res Grp Oligosaccharide Chem, HAS, Egyet Ter 1, H-4032 Debrecen, Hungary.. The CAS is 78-39-7. Through research, I have a further understanding and discovery of 1,1,1-Triethoxyethane
Pseudomonas aeruginosa is a biofilm-forming Gram-negative bacterium and a leading cause of life-threatening nosocomial infections. The polysaccharide synthesis locus (Psl) exopolysaccharide of P. aeruginosa is a key constituent of the defending bacterial biofilm layer and is a promising therapeutic target for resistant species. The Psl exopolysaccharide is built up from repeating pentasaccharide units which contain one alpha- and two beta-mannosidic linkages, and one l -rhamnose and one d -glucose moieties. The preparation of this pentasaccharide was first described by Boons et al. in a 34-step synthesis. Based on their work, we have developed a new and effective pathway for the synthesis of the repeating pentasaccharide unit of the Psl exopolysaccharide. We have succeeded in simplifying the synthesis of the l -rhamnose and the alpha-selective d -mannose building blocks. Furthermore, taking advantage of a chemoselective pre-activation-based beta-mannosylation, we directly prepare a thioglycoside disaccharide donor and use it in the next coupling reaction without further transformation. The pentasaccharide, in the form of a p -methoxyphenyl glycoside, is prepared in 26 steps, which is suitable for biological testing.
Application In Synthesis of 1,1,1-Triethoxyethane. About 1,1,1-Triethoxyethane, If you have any questions, you can contact Demeter, F; Chang, MDT; Lee, YC; Borbas, A; Herczeg, M or concate me.
Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com