I found the field of Biochemistry & Molecular Biology; Chemistry; Polymer Science very interesting. Saw the article Synthesis, characterization and application of copper oxide chitosan nanocomposite for green regioselective synthesis of [1,2,3]triazoles published in 2019.0. Safety of Chalcone, Reprint Addresses Ali, I (corresponding author), Taibah Univ, Dept Chem, Fac Sci, Al Madinah Al Munawarah 30002, Saudi Arabia.. The CAS is 94-41-7. Through research, I have a further understanding and discovery of Chalcone
Chitosan copper (II) oxide nanocomposite was synthesized, characterized and used to synthesize [1,2,3] triazoles. Nanocomposite was characterized by using FTIR, XRD, FESEM, and EDS techniques, which reflected rough morphology. The powerful catalytic activity of hybrid nanocomposite was utilized to synthesize chalcones (3a-p) in relatively high yields (82%-98%) and multicomponent regio-selective cycloaddition of chalones, aryl halides (4), and sodium azide to afford the expected N-2-aryl[1,2,3]triazoles (5a-h) (80%-95% yield) rather than N-1-aryl(1,2,3]-triazoles (6a-h). The performance of nanomaterial was optimized by several variables. The capability of the nanocomposite was compared with previous work and the nanocomposite was found more efficient, economic and reproducible. The hybrid nanocomposite could be easily isolated form the reaction mixture and recycled four times without any significant loss of its catalytic activity. The reported catalyst is an inexpensive for good yields of the triazoles and may be used at industrial production for the reported compounds. (C) 2019 Published by Elsevier B.V.
About Chalcone, If you have any questions, you can contact Khalil, KD; Riyadh, SM; Gomha, SM; Ali, I or concate me.. Safety of Chalcone
Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com