The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. An article , which mentions Electric Literature of 5908-62-3, molecular formula is C3H7NO2S. The compound – 1,1-Dioxo-isothiazolidine played an important role in people’s production and life., Electric Literature of 5908-62-3
There is an increasing amount of literature data showing the positive effects on preclinical antiparkinsonian rodent models with selective positive allosteric modulators of metabotropic glutamate receptor 4 (mGlu4). However, most of the data generated utilize compounds that have not been optimized for druglike properties, and as a consequence, they exhibit poor pharmacokinetic properties and thus do not cross the blood-brain barrier. Herein, we report on a series of N-4-(2,5-dioxopyrrolidin-1-yl) phenylpicolinamides with improved PK properties with excellent potency and selectivity as well as improved brain exposure in rodents. Finally, ML182 was shown to be orally active in the haloperidol induced catalepsy model, a well-established antiparkinsonian model.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Electric Literature of 5908-62-3, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about Electric Literature of 5908-62-3
Reference：
Quinuclidine – Wikipedia,
Quinuclidine | C7H576N | ChemSpider