Simple exploration of 5908-62-3

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Nitrogen-appended N-alkylsulfonamides as inhibitors of gamma-secretase

The synthesis and gamma-secretase inhibition data for a series of nitrogen-appended N-alkylsulfonamides (11-47) are described. Inhibition of brain Abeta in transgenic mice was demonstrated by two of these compounds (23 and 44).

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Reference：
Quinuclidine – Wikipedia,
Quinuclidine | C7H562N | ChemSpider