Tag: M.W=200-250

An article Synthesis, Antimicrobial and Antioxidant Activities of Pyrimidinyl Benzothiazine Carboxamides WOS:000471808200018 published article about GREEN APPROACH; AMINES; ULTRASOUND; ACID in [Tamatam, Rekha; Panga, Siva Sankar; Adivireddy, Padmaja; Venkatapuram, Padmavathi] Sri Venkateswara Univ, Dept Chem, Tirupati, Andhra Pradesh, India; [Grigory, Zyryanov, V; Gundala, Sravya; Nemallapudi, Bakthavatchala Reddy] Ural Fed Univ, Dept Organ & Biomol Chem, Ekaterinburg 620002, Russia; [Vasikarla, Kamala Prasad] Denisco Chem Pvt Ltd, Hyderabad 500055, Telangana, India in 2019.0, Cited 27.0. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7. Quality Control of Chalcone

A variety of pyrimidinyl benzothiazine carboxamides were prepared from benzothiazine carboxylate and 4,6-diaryl/heteroarylpyrimidinyl-2-amines. The compounds having 4-nitro phenyl, 4-pyridinyl and pyrazolyl – pyrimidinyl benzothiazine carboxamide moieties 6 e, 6 i, 6 j, 6 k and 6 m displayed prominent antibacterial activity against Bacillus subtilis. Further, compounds having pyrrolyl, pyrazolyl, pyridinyl and indolyl units 6 f, 6 k, 6 m and 6 n displayed prominent antifungal activity against Aspergillus niger. On the other hand, compounds with electron donating substituents on the aromatic ring (6 b, 6 c) and those with furan moiety (6 g, 6 h and 6 l) displayed very good free radical scavenging activity greater than Ascorbic acid.

About Chalcone, If you have any questions, you can contact Tamatam, R; Panga, SS; Grigory, VZ; Gundala, S; Nemallapudi, BR; Vasikarla, KP; Adivireddy, P; Venkatapuram, P or concate me.. Quality Control of Chalcone

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Hosseini-Sarvari, M; Akrami, Z in [Hosseini-Sarvari, Mona; Akrami, Zahra] Shiraz Univ, Fac Sci, Dept Chem, Shiraz 7194684795, Iran published Visible-light assisted of nano Ni/g-C3N4 with efficient photocatalytic activity and stability for selective aerobic C-H activation and epoxidation in 2020.0, Cited 53.0. Application In Synthesis of Chalcone. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7.

A selective, economical, and ecological protocol has been described for the oxidation of methyl arenes and their analogs to the corresponding carbonyl compounds and epoxidation reactions of alkenes with molecular oxygen (O-2) or air as a green oxygen source, under mild reaction conditions. The nano Ni/g-C3N4 exhibited high photocatalytic activity, stability, and selectivity in the C-H activation of methyl arenes, methylene arenes, and epoxidation of various alkenes under visible- light irradiation without the use of an oxidizing agent and under base free conditions. (C) 2020 Elsevier B.V. All rights reserved.

Application In Synthesis of Chalcone. About Chalcone, If you have any questions, you can contact Hosseini-Sarvari, M; Akrami, Z or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Recently I am researching about HETEROCYCLIC KETENE AMINALS; PALLADIUM-CATALYZED ARYLATION; DIASTEREOSELECTIVE SYNTHESIS; MORPHAN DERIVATIVES; COUPLING REACTIONS; MICHAEL ADDITION; N-ARYLATION; C-N; DESIGN; ENAMINONES, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21662042, 81760621, 21362042, U1202221]; Program for Changjiang Scholars and Innovative Research Team in UniversityProgram for Changjiang Scholars & Innovative Research Team in University (PCSIRT) [IRT17R94]; Natural Science Foundation of Yunnan ProvinceNatural Science Foundation of Yunnan Province [2017FA003]. Category: thiazolidines. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Luo, Q; Huang, R; Xiao, Q; Yao, Y; Lin, J; Yan, SJ. The CAS is 94-41-7. Through research, I have a further understanding and discovery of Chalcone

A general and concise method was developed for the synthesis of 2-amino-4,6-diarylpyridine derivatives 4-6 through the cascade reaction, which includes Michael addition, intramolecular cyclization, aromatization, and/or loss of HNO2, of different types of alpha,beta-unsaturated ketones 1 and 1,1-enediamines 2 and 3 in 1,4-dioxane promoted by the base Cs2CO3 or piperidine. This method is suitable for the efficient parallel synthesis of pyridines. A library of highly functional 2-amino-4,6-diarylpyridine derivatives was easily constructed using the cascade reaction described in this study.

About Chalcone, If you have any questions, you can contact Luo, Q; Huang, R; Xiao, Q; Yao, Y; Lin, J; Yan, SJ or concate me.. Category: thiazolidines

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Recommanded Product: Chalcone. Recently I am researching about BIODIESEL PRODUCTION; PALLADIUM NANOPARTICLES; CONVENIENT SYNTHESIS; CONJUGATE ADDITION; EXTRACT; SOLVENT; BASE; ACID; OIL; NITRATE, Saw an article supported by the UGC, New DelhiUniversity Grants Commission, India. Published in SPRINGER INTERNATIONAL PUBLISHING AG in CHAM ,Authors: Talukdar, A; Deka, DC. The CAS is 94-41-7. Through research, I have a further understanding and discovery of Chalcone

Water hyacinth ash is found to be an efficient and reusable catalyst for the synthesis of beta-amino carbonyl/nitrile compounds by aza-Michael reaction of amines with alpha,beta-unsaturated compounds at room temperature under solvent free condition. Due to low cost of the catalyst, good activity, ease of handling and easy recovery with high yields of the products in short reaction time, easy workup procedure, mild reaction condition, the protocol is highly applicable in synthetic organic chemistry.

Recommanded Product: Chalcone. About Chalcone, If you have any questions, you can contact Talukdar, A; Deka, DC or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Product Details of 94-41-7. In 2019.0 J ORGANOMET CHEM published article about HETEROLYTIC DIHYDROGEN ACTIVATION; ELECTRONIC CONTROL; CHEMISTRY; REDUCTION; BIS(PENTAFLUOROPHENYL)BORANE; STEREOSELECTIVITY in [Woelke, Christian; Daniliuc, Constantin G.; Kehr, Gerald; Erker, Gerhard] Westfalische Wilhelms Univ Munster, Organ Chem Inst, Corrensstr 40, D-48149 Munster, Germany in 2019.0, Cited 56.0. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7.

The [4+2] cycloaddition reaction of the (dimesitylphosphino) cyclopentadienes 5a,b with N-phenyl-maleimide gave the norbornene derivative 9. Its reduction with LiAlH4 produced the N-phenyl-pyrrolidino-annulated system 10. Treatment with Piers’ borane gave the respective P/B FLP 12 as the major product, which cleaved dihydrogen under mild conditions to yield the phosphonium/hydrido borate product 14. Reaction of the phosphino-norbornene 10 with 2 M equiv. of Piers’ borane [HB(C6F5)(2)] followed by exposure to dihydrogen eventually gave the HB(C6F5)(2) adduct 15. This served as a catalyst for the hydrogenation of a series of chalcone derivatives. The system requires a pre-activation period before becoming active for the conjugated enone hydrogenation. (C) 2019 Elsevier B.V. All rights reserved.

About Chalcone, If you have any questions, you can contact Wolke, C; Daniliuc, CG; Kehr, G; Erker, G or concate me.. Product Details of 94-41-7

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Recommanded Product: 94-41-7. I found the field of Pharmacology & Pharmacy; Chemistry very interesting. Saw the article Synthesis and anti-proliferative activity of a novel 1,2,3-triazole tethered chalcone acetamide derivatives published in 2020.0, Reprint Addresses Nagarapu, L (corresponding author), CSIR Indian Inst Chem Technol, Fluoroagrochem Div, Hyderabad 500007, India.. The CAS is 94-41-7. Through research, I have a further understanding and discovery of Chalcone.

A new series of 1,2,3-triazole tethered chalcone acetamide derivatives (7a-c & 8a-r) have been synthesized in excellent yields and their structures were determined by analytical and spectral (FT-IR, H-1 NMR, C-13 NMR HRMS) studies. The newly synthesized derivatives were evaluated for their cytotoxic activity against four human cancer cell lines, such as HeLa (Human cervical cancer), A549 (Human alveolar adenocarcinoma), MCF-7 (Human breast adenocarcinoma) and SKNSH (Human brain cancer). Among them, compound 7c exhibited good anti-proliferation activity with HeLa (IC50 7.41 + 0.8 mu M), SKNSH (IC50 8.68 + 1.1 mu M), MCF-7 (IC50 9.76 + 1.3 mu M) and MDA-MB-231, while compounds 7a and 7b showed promising anti-proliferation against above four human cancer cell lines with IC50 7.95-11.62 mu M, respectively, compared with the standard drug Doxorubicin. We explored the probable key active site and binding mode interactions in HDAC8 (PDB ID:3SFH) and EHMT2 (PDB ID:3K5K) proteins. The docking results are complementary to the experimental observations.

Recommanded Product: 94-41-7. About Chalcone, If you have any questions, you can contact Vanaparthi, S; Bantu, R; Jain, N; Janardhan, S; Nagarapu, L or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

I found the field of Biochemistry & Molecular Biology; Chemistry; Polymer Science very interesting. Saw the article Synthesis, characterization and application of copper oxide chitosan nanocomposite for green regioselective synthesis of [1,2,3]triazoles published in 2019.0. Safety of Chalcone, Reprint Addresses Ali, I (corresponding author), Taibah Univ, Dept Chem, Fac Sci, Al Madinah Al Munawarah 30002, Saudi Arabia.. The CAS is 94-41-7. Through research, I have a further understanding and discovery of Chalcone

Chitosan copper (II) oxide nanocomposite was synthesized, characterized and used to synthesize [1,2,3] triazoles. Nanocomposite was characterized by using FTIR, XRD, FESEM, and EDS techniques, which reflected rough morphology. The powerful catalytic activity of hybrid nanocomposite was utilized to synthesize chalcones (3a-p) in relatively high yields (82%-98%) and multicomponent regio-selective cycloaddition of chalones, aryl halides (4), and sodium azide to afford the expected N-2-aryl[1,2,3]triazoles (5a-h) (80%-95% yield) rather than N-1-aryl(1,2,3]-triazoles (6a-h). The performance of nanomaterial was optimized by several variables. The capability of the nanocomposite was compared with previous work and the nanocomposite was found more efficient, economic and reproducible. The hybrid nanocomposite could be easily isolated form the reaction mixture and recycled four times without any significant loss of its catalytic activity. The reported catalyst is an inexpensive for good yields of the triazoles and may be used at industrial production for the reported compounds. (C) 2019 Published by Elsevier B.V.

About Chalcone, If you have any questions, you can contact Khalil, KD; Riyadh, SM; Gomha, SM; Ali, I or concate me.. Safety of Chalcone

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

An article Novel nicotinonitrile-coumarin hybrids as potential acetylcholinesterase inhibitors: design, synthesis, in vitro and in silico studies WOS:000554057800001 published article about ALZHEIMERS-DISEASE; BIOLOGICAL EVALUATION; DERIVATIVES; DRUG; BIS(2-S-ALKYLPYRIDINES); CHALCONES; DOCKING; MOIETY; QSAR in [Sanad, Sherif M. H.; Mekky, Ahmed E. M.] Cairo Univ, Fac Sci, Chem Dept, Giza 12613, Egypt in 2021.0, Cited 59.0. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7. Recommanded Product: Chalcone

Alzheimer’s disease is a degenerative brain condition that is the leading cause of dementia affecting millions of people around the world. Therapeutic development has focused on the problem of the loss of basal forebrain cholinergic function, as it is the only evidence responsible for brain neurodegeneration in patients with Alzheimer’s disease. Several attempts to improve cholinergic neurotransmission have been investigated by minimizing synaptic degradation of acetylcholine using acetylcholinesterase inhibitors. In the current study, we explore the designing of a new series of nicotinonitrile-coumarin hybrids as potential acetylcholinesterase inhibitors. The new hybrids were prepared utilizing pyridine-2(1H)-thiones as starting precursors. The in vitro acetylcholinesterase (AChE) inhibitory activities were examined for the new nicotinonitrile-coumarin hybrid molecules, when compared with donepezil as a standard drug with IC(50)of 14 nM. Coumarin derivative, linked to 6-(4-nitrophenyl)-4-phenylnicotinonitrile, showed more effective inhibitory activity than the reference donepezil with IC(50)of 13 nM. The free radical-scavenging capabilities against DPPH of the new hybrid derivatives were screened. Additionally, their in vitro cytotoxic activities have been tested against various eukaryotic cells. Furthermore, docking study showed excellent interaction between nicotinonitrile-coumarin hybrids and AChE. [GRAPHICS] .

Recommanded Product: Chalcone. About Chalcone, If you have any questions, you can contact Sanad, SMH; Mekky, AEM or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

SDS of cas: 94-41-7. Authors Morreeuw, ZP; Escobedo-Fregoso, C; Rios-Gonzalez, LJ; Castillo-Quiroz, D; Reyes, AG in ELSEVIER IRELAND LTD published article about in [Morreeuw, Zoe P.] Ctr Invest Biol Noroeste CIBNOR, Ave Inst Politecn Nacl 195, La Paz 23096, Bcs, Mexico; [Escobedo-Fregoso, Cristina; Reyes, Ana G.] CONACYTCIBNOR, Ave Inst Politecn Nacl 195, La Paz 23096, Bcs, Mexico; [Rios-Gonzalez, Leopoldo J.] Univ Autonoma Coahuila UAdeC, Fac Ciencias Quim, Dept Biotecnol, Blvd V Carranza, Saltillo 25280, Coahuila, Mexico; [Castillo-Quiroz, David] Inst Nacl Invest Forest Agr & Pecuarias INIFAP, Carretera Saltillo Zacatecas 9515, Saltillo 25315, Coahuila, Mexico in 2021.0, Cited 126.0. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7

Agave lechuguilla is one of the most abundant species in arid and semiarid regions of Mexico, and is used to extract fiber. However, 85 % of the harvested plant material is discarded. Previous bioprospecting studies of the waste biomass suggest the presence of bioactive compounds, although the extraction process limited metabolite characterization. This work achieved flavonoid profiling of A. lechuguilla in both processed and non-processed leaf tissues using transcriptomic analysis. Functional annotation of the first de novo transcriptome of A. lechuguilla (255.7 Mbp) allowed identifying genes coding for 33 enzymes and 8 transcription factors involved in flavonoid biosynthesis. The flavonoid metabolic pathway was mostly elucidated by HPLC-MS/MS screening of alcoholic extracts. Key genes of flavonoid synthesis were higher expressed in processed leaf tissues than in non-processed leaves, suggesting a high content of flavonoids and glycoside derivatives in the waste biomass. Tar-geted HPLC-UV-MS analyses confirmed the concentration of isorhamnetin (1251.96 ?g), flavanone (291.51 ?g), hesperidin (34.23 ?g), delphinidin (24.23 ?g), quercetin (15.57 ?g), kaempferol (13.71 ?g), cyanidin (12.32 ?g), apigenin (9.70 ?g) and catechin (7.91 ?g) per gram of dry residue. Transcriptomic and biochemical profiling concur in the potential of lechuguilla by-products with a wide range of applications in agriculture, feed, food, cosmetics, and pharmaceutical industries.

About Chalcone, If you have any questions, you can contact Morreeuw, ZP; Escobedo-Fregoso, C; Rios-Gonzalez, LJ; Castillo-Quiroz, D; Reyes, AG or concate me.. SDS of cas: 94-41-7

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Authors Takei, D; Yatabe, T; Jin, XJ; Yabe, T; Mizuno, N; Yamaguchi, K in AMER CHEMICAL SOC published article about ALPHA,BETA-UNSATURATED CARBONYL; GOLD NANOPARTICLES; DEHYDROGENATION; PALLADIUM; OXIDATION; ALDEHYDES; COMBUSTION; AU/CEO2; ENONES; ESTERS in [Takei, Daisuke; Yatabe, Takafumi; Yabe, Tomohiro; Mizuno, Noritaka; Yamaguchi, Kazuya] Univ Tokyo, Dept Appl Chem, Sch Engn, Bunkyo Ku, Tokyo 1138656, Japan; [Jin, Xiongjie] Univ Tokyo, Dept Chem & Biotechnol, Sch Engn, Bunkyo Ku, Tokyo 1138656, Japan in 2020.0, Cited 57.0. Category: thiazolidines. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7

Direct selective desaturation of carbonyl compounds to synthesize alpha,beta-unsaturated carbonyl compounds represents an environmentally benign alternative to classical stepwise procedures. In this study, we designed an ideal CeO2-supported Pd(II)-on-Au nanoparticle catalyst (Pd/Au/CeO2) and successfully achieved heterogeneously catalyzed selective desaturation of cyclohexanones to cyclohexenones using O-2 in air as the oxidant. Besides cyclohexenones, various bioactive enones can also be synthesized from the corresponding saturated ketones under open air conditions in the presence of Pd/Au/CeO2. Preliminary mechanistic studies revealed that alpha-C-H bond cleavage in the substrates is the turnoverlimiting step of this desaturation reaction.

About Chalcone, If you have any questions, you can contact Takei, D; Yatabe, T; Jin, XJ; Yabe, T; Mizuno, N; Yamaguchi, K or concate me.. Category: thiazolidines

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com