Tag: M.W=200-250

An article 4-Aminoindoles as 1,4-bisnucleophiles for diversity-oriented synthesis of tricyclic indoles bearing 3,4-fused seven-membered rings WOS:000471907500016 published article about ONE-POT SYNTHESIS; FACILE SYNTHESIS; 3-COMPONENT REACTIONS; 4-COMPONENT REACTIONS; EXPEDIENT SYNTHESIS; EFFICIENT SYNTHESIS; CATALYST; HYDROGENATION; PROTOCOL; CASCADE in [Chen, Shaomin; Ravichandiran, Palanisamy; El-Harairy, Ahmed; Li, Minghao; Gu, Yanlong] Huazhong Univ Sci & Technol, Sch Chem & Chem Engn, Minist Educ, Key Lab Large Format Battery Mat & Syst, Wuhan 430074, Hubei, Peoples R China; [Queneau, Yves] Univ Claude Bernard, Univ Lyon 1, Univ Lyon,INSA Lyon,CPE Lyon,ICBMS, Inst Chim & Biochim Mol & Supramol,CNRS,UMR 5246, Batiment Lederer,1 Rue Victor Grignard, F-69622 Villeurbanne, France; [Gu, Yanlong] Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Gansu, Peoples R China in 2019.0, Cited 97.0. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7. Name: Chalcone

A straightforward access to tricyclic indoles bearing 3,4-fused seven-membered rings has been established by using 4-aminoindoles as 1,4-bisnucleophiles in three-component reactions. 1H-Azepino[4,3,2-cd]indoles, 4,6-dihydro-1H-azepino[4,3,2-cd]indoles and 1,3,4,6-tetrahydro-5H-azepino[4,3,2-cd]indol-5-ones could thus be synthesized in one pot in moderate to good yields. Beyond opening access to 3,4-fused tricyclic indoles, the use of easily accessible 4-aminoindoles as C,N-1,4-bisnucleophiles also provides a new platform to be used in a diversity-oriented synthesis strategy, fully displaying its benefits of maximizing molecular complexity and reaction diversity.

About Chalcone, If you have any questions, you can contact Chen, SM; Ravichandiran, P; El-Harairy, A; Queneau, Y; Li, MH; Gu, YL or concate me.. Name: Chalcone

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

An article Synthesis of Trifluoromethyl- and Ester Group-Substituted alpha-Carbolines via Iron-Catalyzed Tandem Cyclization Reaction WOS:000526405900036 published article about ONE-POT SYNTHESIS; AMINATION; FLUORINE; INDOLES in [Xu, Yumin; Chen, Xiaoqian; Gao, Yiqin; Wan, Changfeng; Liu, Jin-Biao] Jiangxi Normal Univ, Coll Chem & Chem Engn, Minist Educ, Nanchang 330022, Jiangxi, Peoples R China; [Xu, Yumin; Chen, Xiaoqian; Gao, Yiqin; Wan, Changfeng; Liu, Jin-Biao] Jiangxi Normal Univ, Key Lab Funct Small Organ Mol, Minist Educ, Nanchang 330022, Jiangxi, Peoples R China; [Liu, Jin-Biao] Jiangxi Univ Sci & Technol, Sch Met & Chem Engn, Ganzhou 341000, Peoples R China; [Yan, Zicong; Wang, Zhiyong] Univ Sci & Technol China, Dept Chem, Hefei 230026, Peoples R China in 2020.0, Cited 47.0. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7. Recommanded Product: Chalcone

An efficient approach to prepare trifluoromethyl-alpha-carbolines and ester group-substituted alpha-carbolines via the tandem cyclization reaction of 2-(2-aminophenyl)acetonitriles and trifluoromethyl 1,3-diones or beta,gamma-unsaturated alpha-ketoesters was reported. The transformation proceeded smoothly in the presence of catalytic environmental-benign iron salts, which are used to prepare the desired products in moderate to good yields.

Recommanded Product: Chalcone. About Chalcone, If you have any questions, you can contact Xu, YM; Chen, XQ; Gao, YQ; Yan, ZC; Wan, CF; Liu, JB; Wang, ZY or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

An article Noble-metal-free TiO2 photocatalysis for selective C = C reduction of alpha,beta-enones by CF3SO3H modification WOS:000556422000002 published article about CHEMOSELECTIVE HYDROGENATION; CONJUGATE REDUCTION; ALCOHOLS; OXIDATION; CATALYSIS; TITANIUM; ELECTRON in [Li, Jundan; Wang, Yi; Zhai, Shan; Ma, Dongge] Beijing Technol & Business Univ, Coll Chem & Mat Engn, Dept Chem, Beijing 100048, Peoples R China; [Liu, Anan] Univ Sci & Technol Beijing, Basic Expt Ctr Nat Sci, Beijing, Peoples R China; [Chen, Chuncheng] Chinese Acad Sci, Inst Chem, Key Lab Photochem, Beijing Natl Lab Mol Sci, Beijing, Peoples R China in 2020.0, Cited 26.0. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7. Recommanded Product: Chalcone

The highly selective C = C reduction of alpha,beta-enones was realized by CF3SO3H-modifying noble-metal-free TiO2 photocatalysis. Selectivity for C = C over C = O reduction was dramatically reversed from fair (similar to 42% without CF3SO3H-modifying) to excellent (> 99%) upon only 6 mol% CF3SO3H loading without any noble-metal additive. Attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR) and C-13-nuclear magnetic resonance (NMR) demonstrated that CF3SO3H modification results in the alpha,beta-enone polar C = O bond sitting away from rather than near to the active sites of polar TiO2 catalysts.

Recommanded Product: Chalcone. About Chalcone, If you have any questions, you can contact Li, JD; Liu, AN; Wang, Y; Zhai, S; Ma, DG; Chen, CC or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

An article (+/-)-trans-1,2-Cyclohexanediamine-Based Bis(NHC) Ligand for Cu-Catalyzed Asymmetric Conjugate Addition Reaction WOS:000489178000082 published article about N-HETEROCYCLIC CARBENES; PALLADIUM COMPLEXES; ENANTIOSELECTIVE HYDROSILYLATION; STEREODIRECTING LIGANDS; CHIRAL BENZIMIDAZOLES; ARYLBORONIC ACIDS; METAL-COMPLEXES; AZOLIUM SALTS; REVERSAL; 1,4-ADDITION in [Ishibashi, Azusa; Kamihigashi, Shun; Iwai, Yuuki; Sakaguchi, Satoshi] Kansai Univ, Fac Chem Mat & Bioengn, Dept Chem & Mat Engn, Suita, Osaka 5648680, Japan in 2019.0, Cited 107.0. SDS of cas: 94-41-7. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7

Bis(NHC) ligand precursors, L1, based on trans-1,2-diaminocyclohexane were designed and synthesized. To introduce chirality at the hydroxyamide side arm on the NHC of L1, a chiral beta-amino alcohol, such as enantiopure leucinol, was used. Cu-catalyzed asymmetric conjugate addition reactions of cyclic and acyclic enones with Et2Zn were selected to evaluate the performance of L1 as a chiral ligand. For the reaction of cyclic enone, a combination of [bis(trimethylsilyl)acetylene]-(hexafluoroacetylacetonato)copper(I) (Cu(hfacac)(btmsa)) with a (+/-)-trans-1,2-cyclohexanediamine-based bis(NHC) ligand precursor, (rac; S,S)-L1, which was prepared from (S)-leucinol, was the most effective. Thus, treating 2-cyclohexen-1-one (3) with Et2Zn in the presence of catalytic amounts of Cu(hfacac)(btmsa) and (rac; S,S)-L1 afforded (R)-3-ethylcyclohexanone ((R)-4) with 97% ee. Similarly, use of (rac; R,R)-L1, which was prepared from (R)-leucinol, produced (S)-4 with 97% ee. Conversely, for the asymmetric 1,4-addition reaction of the acyclic enone, optically pure (-)-trans-1,2-cyclohexanediamine-based bis(NHC) ligand precursor, (R,R; S,S)-L1, worked efficiently. For example, 3-nonen-2-one (5) was reacted with Et 2 Zn using the CuOAc/(R,R; S,S)-L1 catalytic system to afford (R)-4-ethylnonan-2-one ((R)-6) with 90% ee. Furthermore, initially changing the counterion of the Cu precatalyst between an OAc and a ClO4 ligand on the metal reversed the facial selectivity of the approach of the substrates. Thus, the conjugate addition reaction of 5 with Et2Zn using the Cu(ClO4)(2)/(R,R; S,S)-L1 catalytic system, afforded (S)-6 with 75% ee.

SDS of cas: 94-41-7. About Chalcone, If you have any questions, you can contact Ishibashi, A; Kamihigashi, S; Iwai, Y; Sakaguchi, S or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

An article Michael Addition of Indoles to Enones Catalyzed by a Cationic Iron Salt WOS:000605598700002 published article about CONJUGATE ADDITION; 1,4-ADDITION; ALKYLATION; PYRROLE; ARYLSILOXANES; COMPLEXES; CHLORIDE; ACIDS in [Inishi, Tsukasa; Hirata, Goki; Nishikata, Takashi] Yamaguchi Univ, Grad Sch Sci & Engn, 2-16-1 Tokiwadai, Ube, Yamaguchi 7558611, Japan in 2021.0, Cited 27.0. Name: Chalcone. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7

Indoles are one of the most valuable nucleophiles in Michael additions catalyzed by a proper Lewis acid. In this paper, we found that a cationic iron salt is effective to carry out the Michael addition of indoles. beta-Mono- and disubstituted enones reacted smoothly with indoles under our conditions. The cationic iron catalyst is very active, and the maximum TON was up to 425. Moreover, cationic iron-catalyzed conditions enabled a chemoselective Michael addition of a substrate possessing both enone and alpha,beta-unsaturated ester moieties.

About Chalcone, If you have any questions, you can contact Inishi, T; Hirata, G; Nishikata, T or concate me.. Name: Chalcone

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Recently I am researching about C-C ACTIVATION; RING-SLIPPAGE; H BOND; CLEAVAGE; BIOMASS; FUELS; ALKENYLATION; CHEMISTRY, Saw an article supported by the National Science FoundationNational Science Foundation (NSF) [CHE1664652]. Category: thiazolidines. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Pannilawithana, N; Yi, CS. The CAS is 94-41-7. Through research, I have a further understanding and discovery of Chalcone

The chelate assistance strategy was devised to promote a highly regioselective catalytic C-C bond activation reaction of saturated and unsaturated carbonyl compounds. The cationic Ru-H complex 1 was found to be an effective catalyst for mediating the coupling reaction of 1,2-disubstituted indoles with alpha,beta-unsaturated aldehydes and ketones, in which the regioselective C-alpha-C-beta activation of the carbonyl substrates has been achieved in forming the 3-alkylindole products. The analogous coupling reaction of indoles with saturated aldehydes and ketones directly led to the C-alpha- C-beta cleavage of the carbonyl substrates in forming the 3-allcylindole products. The coupling reaction of 1,2-dimethylinole with (E)-3-nonen-2-one and 2-propanol-d(8) showed 20-22% of deuterium incorporation to both alpha- and beta-CH2 of the 3-alkylindole product. The coupling reaction of 1,2-dimethylinole with (E)-3-nonen-2-one exhibited the most significant carbon kinetic isotope effect on the alpha-carbon of the product (C-alpha = 1.046). The Hammett plot constructed from the reaction of 1,2-dimethylinole with a series of para-substituted enones p-X-C6H4CH=CHCOCH3 (X = OMe, Me, H, Cl, CF3) showed a modest promotional effect by an electron-donating group (rho = -0.2 +/- 0.1). Several catalytically relevant Ru-H species were detected by NMR from a stoichiometric reaction mixture of the Ru-H complex 1 with 1,2-dimethylindole and (E)-3-nonen-2-one in CD2Cl2. These results support a mechanism of the catalytic coupling reaction via conjugate addition of indoles to enones followed by the C-C bond activation and hydrogenolysis steps.

Category: thiazolidines. About Chalcone, If you have any questions, you can contact Pannilawithana, N; Yi, CS or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Authors Song, T; Zhou, X; Wang, XX; Xiao, JL; Yang, Y in ROYAL SOC CHEMISTRY published article about in [Song, Tao; Zhou, Xin; Wang, Xiaoxue; Yang, Yong] Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biobased Mat, 189 Songling Rd, Qingdao 266101, Peoples R China; [Xiao, Jianliang] Univ Liverpool, Dept Chem, Crown St, Liverpool L69 7ZD, Merseyside, England; [Song, Tao; Zhou, Xin; Wang, Xiaoxue; Yang, Yong] Shandong Energy Inst, Qingdao 266101, Peoples R China in 2021.0, Cited 66.0. Application In Synthesis of Chalcone. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7

A new methodology for the synthesis of alpha-diketones was reported via a one-pot cascade process from aldehydes and ketones catalyzed by a bifunctional iron nanocomposite using H2O2 as a green oxidant in water. The one-pot strategy showed excellent catalytic stability, comprehensive suitability of substrates and important practical utility for directly synthesizing biologically active and medicinally valuable N-heterocycles via an intermittent process.

Application In Synthesis of Chalcone. About Chalcone, If you have any questions, you can contact Song, T; Zhou, X; Wang, XX; Xiao, JL; Yang, Y or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Recommanded Product: 94-41-7. In 2020.0 ORGANOMETALLICS published article about ASYMMETRIC REDUCTION; EFFICIENT CATALYST; KETONES; ALDEHYDES; HYDROSILYLATION; COMPLEXES; HYDRIDE; RUTHENIUM; POLY(SILYLETHER)S; HYDROGENATION in [Vijjamarri, Srikanth; O’Denius, Timothy M.; Yao, Bin; Kubatov, Alena; Du, Guodong] Univ North Dakota, Dept Chem, Grand Forks, ND 58202 USA in 2020.0, Cited 81.0. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7.

Hydroboration of carbonyl compounds is an important transformation in organic chemistry, and a growing interest in catalysis has focused on abundant and nontoxic base metals. Herein we describe an efficient salen manganese catalyst for the hydroboration of a broad range of carbonyl compounds with pinacolborane. The catalytic reactions proceeded rapidly (>99% conversion in <5 min) at room temperature with very low catalyst loadings. High turnover frequency (up to 5700 h(-1)) was observed under these conditions. Several synthetically important functional groups were tolerated, and chemoselective hydroboration of aldehydes over ketones was achieved. The H/D kinetic isotopic effect of borane was determined to be 2.3. The Hammett correlation plot of a series of para-substituted acetophenone substrates, p-X-C6H6COCH3 (X = H, Me, OMe, NO2, Cl, Br, and CF3) yielded a positive slope of rho = +0.99. The crossover products were detected in the competition reaction of catecholborane and deuterated pinacolborane with acetophenone. The findings indicated a potential borane-mediated pathway that could account for the observation of the crossover products. Recommanded Product: 94-41-7. About Chalcone, If you have any questions, you can contact Vijjamarri, S; O’Denius, TM; Yao, B; Kubatov, A; Du, GD or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

An article Introducing the Dihydro-1,3-azaboroles: Convenient Entry by a Three-Component Reaction, Synthetic and Photophysical Application WOS:000618171900042 published article about RING-CLOSING METATHESIS; RAY CRYSTAL-STRUCTURE; 1,2-AZABOROLYL COMPLEXES; MULTICOMPONENT REACTIONS; AZABOROLYL COMPLEXES; SANDWICH COMPLEXES; B-N; BORON; LIGAND; POLYMERIZATION in [Li, Jun; Daniliuc, Constantin G.; Kartha, Kalathil K.; Fernandez, Gustavo; Kehr, Gerald; Erker, Gerhard] Westfalische Wilhelms Univ Munster, Organ Chem Inst, D-48149 Munster, Germany in 2021.0, Cited 68.0. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7. COA of Formula: C15H12O

The (Fmes)BH2 center dot SMe2 reagent (7) reacts sequentially with an acetylene and, e.g., xylylisonitrile in a convenient three-component reaction to give a series of unprecedented dihydro-1,3-azaborole derivatives 16. The tolane-derived example 16a was deprotonated and used as a ligand in organometallic chemistry. Compounds 16 served as the starting materials for the straightforward synthesis of various dihydro-1,3-azaborinine derivatives by treatment with an isonitrile. Several diaryldihydro-1,3 azaboroles showed interesting photophysical properties such as aggregation-induced emission and high fluorescence quantum yields.

COA of Formula: C15H12O. About Chalcone, If you have any questions, you can contact Li, J; Daniliuc, CG; Kartha, KK; Fernandez, G; Kehr, G; Erker, G or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Quality Control of Chalcone. In 2020.0 GREEN CHEM published article about MOLECULAR-OXYGEN; GEM-DIHYDROPEROXIDES; EFFICIENT SYNTHESIS; ANTHRAQUINONE; 2-PROPANOL; ACTIVATION; OXIDATION; ACID in [Zhang, Yuannian; Yang, Xin; Liang, Dong; Huang, Dejian] Natl Univ Singapore, Dept Chem, Food Sci & Technol Program, Singapore 117543, Singapore; [Tang, Haidi; Wu, Jie] Natl Univ Singapore, Dept Chem, Singapore 117543, Singapore in 2020.0, Cited 33.0. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7.

Pyrenediones (PYDs) are efficient photocatalysts for three oxygenation reactions: epoxidation of electron deficient olefins, oxidative hydroxylation of organoborons, and oxidation of sulfides via in situ generation of H2O2 under visible light irradiation, using oxygen as a terminal oxidant and IPA as a solvent and a hydrogen donor.

Quality Control of Chalcone. About Chalcone, If you have any questions, you can contact Zhang, YN; Yang, X; Tang, HD; Liang, D; Wu, J; Huang, DJ or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com