Tag: M.W:200-300

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: Bromoferrocene, is researched, Molecular C10BrFe, CAS is 1273-73-0, about Reactions of haloferrocenes with organolithium compounds.Application In Synthesis of Bromoferrocene.

Reactions of BuLi or PhLi with chloroferrocene (I), 1,1′-dichloroferrocene (II), and bromoferrocene (III) were investigated. I (0.802 g) in 25 ml Et2O treated with 200 millimoles. BuLi in Et2O and quenched with H2O gave 0.033 g ferrocene (IV) and 0.534 g I. Lithiation of 0.870 g I followed by carbonation and esterification afforded 0.398 g Me 2-chloroferrocenecarboxylate (V) and 0.051 g di-Me 2-chloroferrocene-1,1′-dicarboxylate. Similarly I and PhLi gave 21% V. Heating I and PhLi 4.5 hr and quenching with H2O afforded 50% I, 8% IV, and 24% phenylferrocene (V). However no ferrocyne was detected in attempted capture with some dienes. Similarly lithiation of II followed by carbonation and esterification gave meso and racemic forms, m. 117-17.5° and 110-11°, of di-Me 2,2′-dichloroferrocenedicarboxylates in 48% yield. The reaction of III with BuLi at -78° followed by quenching with H2O gave 36% IV and 37% IV, whereas lithiation at room temperature gave 99% IV. Treating III with PhLi also afforded small amount of V. Lithiation at the 2-position is favored in the case of the Cl compound whereas Br-Li exchange is favored in the case of the Br compound I lithiated with BuLi and treated with HgBr2 gave bis(2-chloroferrocenyl)mercury (VI), m. 219-20°. Similarly bis(2,1′-dichloroferrocenyl)mercury was prepared Attempted capture of ferrocyne by heating VI in tetracyclone ended in failure, the product being IV.

If you want to learn more about this compound(Bromoferrocene)Application In Synthesis of Bromoferrocene, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(1273-73-0).

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: Bromoferrocene, is researched, Molecular C10BrFe, CAS is 1273-73-0, about Reactions of haloferrocenes. II. Kinetic studies of the reaction of haloferrocene with copper(1) chloride-pyridine complex.Recommanded Product: Bromoferrocene.

The reaction of bromoferrocene with CuCl-C5H5N complex was second-order; first-order in each of bromoferrocene and CuCl-C5H5N. Competitive reactions between bromoferrocene and PhBr indicated that bromoferrocene was 103 times more reactive than PhBr in the halogenexchange reaction. The effects of pyridine bases on the halogen-exchange reaction of bromoferrocene were examined, and the trend of results was different from that of PhBr.

If you want to learn more about this compound(Bromoferrocene)Recommanded Product: Bromoferrocene, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(1273-73-0).

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Labande, Agnes; Daran, Jean-Claude; Long, Nicholas J.; White, Andrew J. P.; Poli, Rinaldo researched the compound: Bromoferrocene( cas:1273-73-0 ).Category: thiazolidine.They published the article 《Rhodium(III) and ruthenium(II) complexes of redox-active, chelating N-heterocyclic carbene/thioether ligands》 about this compound( cas:1273-73-0 ) in New Journal of Chemistry. Keywords: crystal structure rhodium ruthenium ferrocenyl NHC thioether complex preparation; mol structure rhodium ruthenium ferrocenyl NHC thioether complex; rhodium ruthenium ferrocenyl NHC thioether complex preparation electrochem property. We’ll tell you more about this compound (cas:1273-73-0).

Half-sandwich rhodium(III) and ruthenium(II) complexes bearing a new redox-active ferrocenyl NHC-thioether ligand have been prepared The synthesis of ferrocenyl thioether-imidazolium salts was carried out via intermediate FcSCH2CH2Cl using an improved procedure. Rhodium(III) complex and ruthenium(II) complex were obtained in good yields and were fully characterised by NMR spectroscopy, x-ray diffraction anal. and electrochem. Rhodium(III) complex shows a complex ABCD system by 1H NMR, which denotes conformational rigidity due to the presence of several bulky groups. Electrochem. anal. by cyclic voltammetry reveals reversible redox behavior about the iron center in both complexes, and indicates electronic communication between iron and rhodium or ruthenium.

If you want to learn more about this compound(Bromoferrocene)Category: thiazolidine, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(1273-73-0).

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: Bromoferrocene( cas:1273-73-0 ) is researched.Recommanded Product: Bromoferrocene.Carre, Francis; Guerin, Christian; Henner, Bernard J. L.; Uerpmann, Carsten published the article 《Synthesis, structure and reactivity study of 1,1′-bis(N-tert-butyl-N-hydroxyamino)ferrocene》 about this compound( cas:1273-73-0 ) in Journal of Organometallic Chemistry. Keywords: ferrocene hydroxyamino disubstituted preparation structure oxidation; crystal structure ferrocene hydroxyamino disubstituted; mol structure ferrocene hydroxyamino disubstituted; ESR oxidized disubstituted ferrocene hydroxyamino aminoxyferrocene radical. Let’s learn more about this compound (cas:1273-73-0).

The synthesis of 1,1′-bis(N-tert-butyl-N-hydroxyamino)ferrocene (1) is described, and the x-ray anal. showed eclipsed positions of the two tert-butylhydroxyamino groups. This structure can be explained by the interactions of the hydroxyl hydrogens with the N atoms of the other tert-butylhydroxyamino group. This interaction is maintained in solution and may explain that the oxidation of 1 using Ag2O gave a decomposition reaction instead of the expected 1,1′-bis(N-tert-butylaminoxy)ferrocene. The ESR spectrum of an oxidized solution of 1 showed a 1:1:1 triplet, but it corresponded only to traces of an N-O• radical. Cyclic voltammograms of 1 showed that it is more easily oxidized than ferrocene and less easily than 1,1′-diaminoferrocene, indicating that chem. oxidation of 1 occurs in the ferrocenyl part of the mol., followed by rapid decomposition

If you want to learn more about this compound(Bromoferrocene)Recommanded Product: Bromoferrocene, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(1273-73-0).

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: quinoliniumhydrogensulphate(SMILESS: [O-]S(=O)(O)=O.C12=CC=C[NH+]=C1C=CC=C2,cas:530-66-5) is researched.HPLC of Formula: 7524-52-9. The article 《Separation of quinaldine from a ternary mixture with quinoline and isoquinoline》 in relation to this compound, is published in Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation). Let’s take a look at the latest research on this compound (cas:530-66-5).

The solubility relations of the monophosphate and bisulfate salts of quinaldine (I), quinoline (II), and isoquinoline (III) were studied. The solubility of the monophosphate of III in H2O at 25° is 6.7 times that of I or II. The solubility of the bisulfates of I and II was studied at 0-50° and 75-95% EtOH. At 10° and 85% EtOH, the solubility ratio of II to I is 3.8. I, 96% pure, was obtained from a mixture of I, II, and III by the following method. To 500 g. of a 1:1 mixture I (32%), II (20%), and III (40%) in MeOH was added 1 equivalent of H3PO4 (at <25°). To the precipitated salt was added just enough H2O to dissolve all of the phosphate of III. The remaining salt was decomposed in 20% NaOH yielding a 1:1 mixture of I and II. This was dissolved in 85% EtOH (1:1 ratio) and 1 equivalent of H2SO4 was added. The precipitated salt was recrystallized from 85% EtOH at 10°, decomposed with 10% base, extracted with benzene, and distilled to yield 58.8% I. If you want to learn more about this compound(quinoliniumhydrogensulphate)Synthetic Route of C9H9NO4S, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(530-66-5).

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

Category: thiazolidine. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: Bromoferrocene, is researched, Molecular C10BrFe, CAS is 1273-73-0, about Synthesis and characterization of functionalized ferrocenylsilanes bearing a bulky substituent. Author is Sasamori, Takahiro; Kobayashi, Megumi; Nagahora, Noriyoshi; Sugiyama, Yusuke; Tokitoh, Norihiro.

Several types of overcrowded ferrocenylsilanes, Tbt(Fc)SiX2(Tbt = 2,4,6-tris[bis(trimethylsilyl)methyl]phenyl, Fc = ferrocenyl, X = H, OH, Br) were synthesized and characterized. In addition, DFT calculations for ferrocenylsilanediol systems indicated the existence of the intramol. hydrogen bonding between the Fe atom and H-O moiety in Tbt(Fc)Si(OH)2.

If you want to learn more about this compound(Bromoferrocene)Category: thiazolidine, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(1273-73-0).

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

Category: thiazolidine. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: (R)-4-(tert-Butyl)-2-(5-(trifluoromethyl)pyridin-2-yl)-4,5-dihydrooxazole, is researched, Molecular C13H15F3N2O, CAS is 1428537-19-2, about Enantioselective total synthesis of the highly selective sphingosine-1-receptor VPC01091 by the Heck desymmetrization of a non-activated cyclopentene-fused spiro-pyrrolidinone. Author is Khan, Ismat Ullah; Kattela, Shivashankar; Hassan, Abbas; Correia, Carlos Roque Duarte.

A novel, efficient and enantioselective Heck-Matsuda desymmetrization of non-activated cyclopentene-fused spiro-pyrrolidinones was developed. The reaction provided the Heck products in good to excellent yields and selectivities and tolerated a variety of functional groups in arenediazonium tetrafluoroborates (12 examples) with respect to its electronics and substitution patterns. This methodol. was successfully applied in the concise enantioselective total synthesis of VPC01091 (I), a drug candidate for the treatment of multiple sclerosis.

If you want to learn more about this compound((R)-4-(tert-Butyl)-2-(5-(trifluoromethyl)pyridin-2-yl)-4,5-dihydrooxazole)Category: thiazolidine, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(1428537-19-2).

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 2-(7-Bromo-1H-indol-3-yl)acetic acid(SMILESS: O=C(O)CC1=CNC2=C1C=CC=C2Br,cas:63352-97-6) is researched.Related Products of 3326-71-4. The article 《A New Approach To Predict the Biological Activity of Molecules Based on Similarity of Their Interaction Fields and the logP and logD Values: Application to Auxins》 in relation to this compound, is published in Journal of Chemical Information and Computer Sciences. Let’s take a look at the latest research on this compound (cas:63352-97-6).

The activity of a biol. compound is dependent both on specific binding to a target receptor and its ADME (Absorption, Distribution, Metabolism, Excretion) properties. A challenge to predict biol. activity is to consider both contributions simultaneously in deriving quant. models. We present a novel approach to derive QSAR models combining similarity anal. of mol. interaction fields (MIFs) with prediction of logP and/or logD. This new classification method is applied to a set of about 100 compounds related to the auxin plant hormone. The classification based on similarity of their interaction fields is more successful for the indole than the phenoxy compounds The classification of the phenoxy compounds is however improved by taking into account the influence of the logP and/or the logD values on biol. activity. With the new combined method, the majority (8 out of 10) of the previously misclassified derivatives of phenoxy acetic acid are classified in accord with their bioassays. The recently determined crystal structure of the auxin-binding protein 1 (ABP1) enabled validation of our approach. The results of docking a few auxin related compounds with different biol. activity to ABP1 correlate well with the classification based on similarity of MIFs only. Biol. activity is, however, better predicted by a combined similarity of MIFs + logP/logD approach.

In some applications, this compound(63352-97-6)Computed Properties of C10H8BrNO2 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

Electric Literature of C10BrFe. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: Bromoferrocene, is researched, Molecular C10BrFe, CAS is 1273-73-0, about Copper bis(2,2,6,6-tetramethyl-3,5-heptanedionate) catalyzed synthesis of N-substituted ferrocenes. Author is Purecha, Vishal H.; Nandurkar, Nitin S.; Bhanage, Bhalchandra M.; Nagarkar, Jayashree M..

An efficient catalytic protocol for the Ullmann-type coupling reaction of both bromo and iodoferrocene with heterocyclic amines using a stable and well defined copper bis(2,2,6,6-tetramethyl-3,5-heptanedionate) complex has been developed. The protocol was applicable for the synthesis of wide variety of N-substituted ferrocenes and the desired products were obtained in good to excellent yields.

In some applications, this compound(1273-73-0)Electric Literature of C10BrFe is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called The structural systematics of protonation of some important nitrogen-base ligands. III. Some (univalent) anion salts of some hindered unidentate nitrogen bases, published in 2006, which mentions a compound: 530-66-5, mainly applied to crystal structure nitrogen base hindered unidentate salt; mol structure nitrogen base hindered unidentate salt, Synthetic Route of C9H9NO4S.

Recent structural studies of salts of the 2,2,6,6-tetramethylpiperidinium cation [tmpH]+ (chloride, bromide; thiocyanate) present as interesting dimeric or polymeric associations linked by pairs of directional H-bonds from the cationic = NH+2 moieties to ‘two-coordinate’ anions. Present single crystal x-ray studies have characterized the iodide, perchlorate, nitrate and trifluoroacetate complexes, all, like those of the preceding studies, [tmpH]+X- (anhydrous). A variety of forms are found: the nitrate compound is dimeric [[tmpH](O·NO·O)2[Htmp]], the trifluoroacetate compound being similar in form while the iodide and perchlorate salts are mixtures of dimers (with the anions essentially single atom bridges) and single-stranded helical polymers, the stoichiometric ratio of these being 1:1 and 2:1 in terms of [tmpH]X formula units, resp. A study of 4-keto-2,2,6,6-tetramethylpiperidinium thiocyanate shows it to be a dimer [[OtmpH](SCNNSC)[HtmpO]], unlike its previously studied chloride analog which is a cyclic tetramer. A new P21/n phase of diisopropylammonium chloride, derivative of the previously described P212121 and P21 forms, is reported, together with descriptions of protonated salts of the other hindered unidentate bases 2,6-lutidine (as the chloride salt), quinoline (as the perchlorate, trifluoroacetate, hexachlorostannate and bisulfate salts) and 2-quinaldine (as the chloride (anhydrous and monohydrate) and hexachlorostannate salts), all displaying arrays derivative of ion-pair formation (extended by anion-anion H-bonds as well in the bisulfate salt) and, in the case of the aromatic bases, dominated by parallel stacking.

In some applications, this compound(530-66-5)Synthetic Route of C9H9NO4S is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com